Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei : Deviation from the Norm
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چکیده
منابع مشابه
Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei: Deviation from the Norm
The trimethoprim and sulfamethoxazole combination, co-trimoxazole, plays a vital role in the treatment of Burkholderia pseudomallei infections. Previous studies demonstrated that the B. pseudomallei BpeEF-OprC efflux pump confers widespread trimethoprim resistance in clinical and environmental isolates, but this is not accompanied by significant resistance to co-trimoxazole. Using the excluded ...
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ژورنال
عنوان ژورنال: mBio
سال: 2017
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.01357-17